By Jonathan Korostoff, D.M.D., Ph.D.

Upon initial presentation, the patient was a normally developed 23-year-old Caucasian male with a history of ectodermal dysplasia. He had undergone orthodontic treatment as an adolescent and his desire was to replace his missing teeth with implant-supported fixed restorations.

Figure 1

Upon review of his medical history and extraoral examination (Figure 1) it was evident that the sole manifestation of his ectodermal dysplasia was agenesis of numerous teeth. Beyond this, he denied any other medical problems and was not taking medications. The patient did exhibit a moderately high lipline.

Figure 2

Intraoral examination (Figure 2) revealed the absence of tooth #’s 1, 4, 5, 7, 10, 12, 16, 17, 20, 28, 29 and 32. Clinical evidence of possible horizontal alveolar ridge deficiencies was detected in site #’s 5, 7, 10, 12, 20, 28 and 29. Tooth #13 was over-erupted necessitating reduction of the buccal cusp to create space for an implant-supported crown.

Figure 3

The patient exhibited mild gingivitis in the absence of any other periodontal pathology (periodontal charting in Figure 3). Both the maxillary and mandibular arches were U-shaped (Figure 4).

Figure 5

Radiographic evaluation (Figure 3) demonstrated a radiolucency at the apex of #25 and insufficient ridge height for implant placement in site #4. The lack of crestal bone height at this site was confirmed via a cone-beam CT scan that also showed a deficiency in ridge width in site #s 7 and 10.

Our  Treatment Plan

With this diagnostic information, a treatment plan was presented to the patient that included endodontic therapy on #25, the placement of implants in site #’s 4, 7, 10, 12, 20, 28 and 29 that would all be restored as single-unit crowns and ceramic veneers on #’s 6, 8, 9 and 11.

It was explained to the patient that a lateral window sinus elevation was necessary for implant placement in site #4 and horizontal ridge augmentation in site #’s 7 and 10. The patient accepted the proposed plan and after an adult prophylaxis, the treatment was initiated.

Figure 5

It was decided that the implants would be placed utilizing a computer-generated tooth-supported guide designed using Simplant (Figure 5) and that the sinus lift and horizontal ridge augmentations would be done coincident with implant placement. On the day of surgery (Figure 5), flaps were elevated and a lateral window sinus lift in site #4 was performed and grafted with BioOss that had been hydrated with recombinant platelet-derived growth factor (GEM-21).

Straumann Implants

Straumann bone level implants were then inserted as follows: site #’s 4 (4.1 x 10.0 mm), 7 (3.3 x 10.0 mm), 10 (3.3 x 10.0 mm), 12 (3.3 x 8.0 mm), 20 (3.3 x 8.0 mm), 28 (3.3 x 8.0 mm) and 29 (3.3 x 10.0 mm). Coverscrews were placed on all of the implants.

Figure 6

The same graft materials used in the sinus were utilized to augment the deficient ridge in site #’s 7 and 10. All of the grafts were covered with BioGide membranes. Goretex sutures were used to achieve tension-free primary closure of all of the flaps. After four months of uneventful healing, the implants were exposed and healing abutments were placed (Figure 6).

The maxillary implants were exposed using a carbon dioxide laser while the mandibular fixtures were uncovered via elevation of flaps. Two months after implant placement, the implant in site #4 was found to be mobile and was removed. The residual osteotomy was grafted with freeze-dried bone allograft and allowed to heal for three months at which time a Straumann bone level 4.1 x 10.0 mm implant was placed as a one-stage procedure.

The Restorative Phase

Figure 7

After four months of healing, all of the implants had successfully integrated and the restorative phase of therapy was begun. Impressions were made of the implants and custom abutments were fabricated (Figure 7). Tooth #’s 6, 8, 9 and 11 were prepared for ceramic veneers, an impression made and the teeth provisionalized.

Figure 8

Temporary crowns were placed on the implants. The patient was pleased with esthetics of the temporary restorations so the laboratory was asked to fabricate the final crowns and veneers that were then cemented in place (Figure 8).

Figure 9

Figure 9 shows a comparison of the patient’s pre- and post-treatment photographs, post-treatment radiographs and extraoral photograph. All of the implants appeared well-integrated and there was no evidence of periimplant soft tissue pathology. The patient was extremely satisfied with the function and esthetics of the final restorations.

The patient was treated in the post-graduate periodontics and periodontal prosthesis Amsterdam-Cohen Clinic of the University of Pennsylvania School of Dental Medicine. The treatment was carried out by Drs. Vico Cambra and Vu Dang La under the supervision of Drs. Howard Fraiman and Jonathan Korostoff.

 

(Dr. Jonathan Korostoff wrote this case study for other oral health care providers for our Dental Treatment Center Newsletter. He is the Professor of Periodontics and the 
Director, Master of Science in Oral Biology Program at Penn Dental Medicine. He is the lead of the NFED Dental Treatment Center at Penn Dental Medicine. Read more of why Dr. Korostoff likes treating individuals affected by ectodermal dysplasias.)

One comment on “A Case Study: Dental Implants in a 23-Year-Old With Ectodermal Dysplasia”

  1. 1
    K on August 12, 2018

    Hi. How do I go about being a case study. 36yr old female. Devasting life and confidence. Don’t know where to turn. Do not go out and lost a lot of weight in 2yrs gone from Size 14 to size 4-6 so I will not last forever this way. I don’t know who to contact. I have 2 young son’s partner and my life is miserable and I think there better off without me. Never being able to wear lipstick and I’m into fashi on etc a lot as had first tooth out in bootie front at age 11 so being right in front I was always being looked at when talking and in the last 7yrs it’s got so bad. I don’t go out hardly but in the last 8 months has got very bad as I have not been outside at all since Jan-Feb this year. It’s not just a smile it’s life. I know nothing will come off this but I can not sleep I can not cope. I can’t do this anymore. With the cost being £30,000 I’ve only got one sixth of that to pay So there’s No hope at all. I need a dentist to take me on as case study and I could pay one sixth straight away.

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